Vitamin B5 -- Pantothenic Acid

 

Disease Treatment

Wound healing:

Intake of pantothenic acid orally and application of pantothenol ointment to the skin have been shown to accelerate the closure of skin wounds and increase the strength of scar tissue in animals.

Adding calcium-D-pantothenate to cultured human skin cells with an artificial wound increased the number and speed or migrating skin cells, which would likely accelerate wound healing. However, little data exists in humans to support the findings of accelerated wound healing in cell culture and animal studies.

High cholesterol:

A certain pantothenic acid derivative called pantethine has been reported by a number of investigators to have an effect on cholesterol lowering. Pantethine is actually two molecules of pantetheine joined by a disulfide bond. In the synthetic pathway of coenzyme A (CoA), pantethine is closer to CoA than pantothenic acid, and is the functional component of CoA and acyl carrier proteins.

Several studies found doses of 900 mg, 300 mg three times a day, of pantethine to be significantly more effective than placebo in lowering total cholesterol and triglyceride levels in the blood of both diabetic and non-diabetic individuals.

Pantethine is not a vitamin, but it is a derivative of pantothenic acid. The decision to use pantethine to treat elevated blood cholesterol or should be made with your doctor, and have a followup visit fairly soon after starting to observe the effects.