Vitamin B5 -- Pantothenic Acid
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Disease Treatment
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Wound healing:
Intake of pantothenic acid orally and application of
pantothenol ointment to the skin have been shown to accelerate the closure
of skin wounds and increase the strength of scar tissue in animals.
Adding calcium-D-pantothenate to cultured human skin cells
with an artificial wound increased the number and speed or migrating skin
cells, which would likely accelerate wound healing. However, little data
exists in humans to support the findings of accelerated wound healing
in cell culture and animal studies.
High cholesterol:
A certain pantothenic acid derivative called pantethine
has been reported by a number of investigators to have an effect on cholesterol
lowering. Pantethine is actually two molecules of pantetheine joined by
a disulfide bond. In the synthetic pathway of coenzyme A (CoA), pantethine
is closer to CoA than pantothenic acid, and is the functional component
of CoA and acyl carrier proteins.
Several studies found doses of 900 mg, 300 mg three times
a day, of pantethine to be significantly more effective than placebo in
lowering total cholesterol and triglyceride levels in the blood of both
diabetic and non-diabetic individuals.
Pantethine is not a vitamin, but it is a derivative of
pantothenic acid. The decision to use pantethine to treat elevated blood
cholesterol or should be made with your doctor, and have a followup visit
fairly soon after starting to observe the effects.
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